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近年来,由于应用超声检查及羊水分析,使产前诊断取得了惊人的进展,已成为胎儿治疗的巨大推动力。妊娠早期发现染色体异常、先天畸形或先天代谢异常,已作为治疗性终止妊娠的适应证,为人类优生优育提供了物质保证。但是实行胎儿治疗则是刚刚起步,可治疗的胎儿疾病非常有限。随着对羊水循环、代谢的深入了解,通过羊膜腔进行内、外科治疗,确有了某种程度的进展,现就有关问题说明如下。一、羊膜腔给药进行胎儿内科治疗(一)羊膜腔注射利凡诺引产:已广泛应用于临床,目前主要用于妊娠14~24周要求终止妊娠或因某种疾病不宜继续妊娠者,另外也常用于死胎引产。羊膜腔注药后,约有96%的病例于72小时左右结束妊娠。本法具有简便、有效和安全性较大等优点。
In recent years, due to the application of ultrasound and amniotic fluid analysis, made astonishing advances in prenatal diagnosis, has become a tremendous impetus for fetal treatment. Early pregnancy found chromosomal abnormalities, congenital malformations or anomalies, has been used as indications for the termination of treatment of pregnancy for human prenatal and postnatal care provided a material guarantee. However, the implementation of fetal treatment is just beginning, treatable fetal disease is very limited. With the amniotic fluid circulation, metabolism, in-depth understanding of the surgical treatment through the amniotic cavity, do have some degree of progress, the relevant issues are described below. First, amniotic drug delivery for fetal medical treatment (A) Amniotic injection of Rivanol Induction of labor: has been widely used in clinical, is currently mainly used for 14 to 24 weeks of pregnancy require termination of pregnancy or due to a disease should not continue with pregnancy, the other Also commonly used in stillbirth induction. After injection of amniotic cavity, about 96% of cases in about 72 hours to end the pregnancy. This law is simple, effective and safe and so on.