细胞凋亡(apoptosis)是一种由基因调控的,具有特征性的细胞主动死亡过程。细胞凋亡与细胞增殖组成一对矛盾统一体,贯穿生命活动的始终。它们共同决定着细胞和组织的基本特征和命运。随着对细胞凋亡分子机制认识的深入,不仅有助于阐明许多长期困扰人类的疾病,而且还可通过诱导细胞凋亡,为一些疾病的治疗提供新的途径。现就肝纤维化逆转过程中肝星状细胞(hepatic stellate cells,HSCs)凋亡研究进展作一简述。 Apoptosis (apoptosis) is a gene-controlled and characteristic cell death process. Apoptosis and cell proliferation constitute a pair of contradictory unity, throughout the life activity has always been. Together, they determine the basic characteristics and fate of cells and tissues. With the understanding of the molecular mechanism of apoptosis, not only help to clarify many long-term human diseases, but also can provide a new way for the treatment of some diseases by inducing apoptosis. The progress of apoptosis of hepatic stellate cells (HSCs) during the process of liver fibrosis reversal is briefly reviewed.