在淋巴细胞分裂中,c-myc 基因的特殊作用是知道的。当促细胞分裂剂加入到 T 淋巴细胞时,c-myc 基因转录开始发生,并认为在G0期向 G_1期转化时,转录物最为显著。但是 c-myc 转录物的累积不足以说明 T 淋巴细胞增殖。细胞增殖时,c-myc 诱导是否需要,这是不清楚的。作者提出这个问题,企图用反意寡聚体抑制 c-myc 蛋白表达。在这些实验中,使用新鲜的 The specific role of the c-myc gene is known in lymphocyte division. When cytokines are added to T lymphocytes, transcription of the c-myc gene begins and it is believed that transcripts are most pronounced during the G0 phase transition to the G_1 phase. However, the accumulation of c-myc transcripts is not sufficient to account for T lymphocyte proliferation. It is unclear whether c-myc induction is required for cell proliferation. The authors raise this issue in an attempt to inhibit c-myc protein expression with antisense oligomers. In these experiments, fresh ones were used