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对４４例急性白血病患者进行了血浆Ⅱ：Ｃ和Ⅴ：Ｃ的研究。正常对照组Ⅱ：Ｃ活性为９９．８３±２９．１９（％），Ⅴ：Ｃ为１０１．５０±３９．７４（％）。疾病活动期、有出血倾向时Ⅱ：Ｃ降低；当外周血幼稚细胞＞６０％时，Ⅱ：Ｃ降低更明显为５９．１９±２４．５５（％）；以上变化有统计学意义（Ｐ＜０．０５）。缓解期，Ⅱ：Ｃ水平有所恢复，但未达正常。Ⅴ：Ｃ仪表现在疾病活动期活性高于正常，为１５２．８４±７７．４８（％）（Ｐ＜０．０１），在其它组变化不明显。研究结果显示Ⅱ：Ｃ与急性白血病出血倾向相关；Ⅴ：Ｃ则可能与白血病细胞促凝活性相关。
The plasma II:C and V:C were studied in 44 patients with acute leukemia. The normal control group II: C activity was 99.83±29.19 (%) and V:C was 101.50±39.74 (%). II:C decreased when the disease was active and with bleeding tendency; when the peripheral blood immature cells were >60%, the decrease of II:C was more pronounced as 59.19±24.55(%); the above changes were statistically significant (P< 0.05). During the remission period, the II:C level has recovered but has not reached normal levels. The activity of V:C meters was higher than normal at 152.84±77.48(%) (P<0.01), but not in other groups. The results of the study show that II:C is associated with bleeding tendency in acute leukemia; V:C may be associated with procoagulant activity in leukemia cells.