1950年前,系统性红斑狼疮(SLE)是一种迅速致死的疾病。皮质激素的应用、早期诊断和其他药物的发展延长了患者的生存期。作者对81例病人作了5年随访,平均发病年龄为32岁,平均病程6年。其中73例(90％)接受强的松治疗,平均每日剂量18.1毫克。40例(49％)有肾脏损害的临床表现,21例(26％)发生不同程度的感染,6例(7％)有心肌梗死。5年中共有11例死亡。平均年龄44岁,平均病程4.2年。死亡病例按其 Before 1950, systemic lupus erythematosus (SLE) was a rapidly fatal disease. The use of corticosteroids, early diagnosis and the development of other drugs have extended the patient’s survival. The authors of 81 patients were followed up for 5 years, the average age of onset was 32 years, the average duration of 6 years. Of these, 73 (90%) received prednisone, with an average daily dose of 18.1 mg. Forty cases (49%) had clinical manifestations of renal damage, 21 (26%) had varying degrees of infection and 6 (7%) had myocardial infarction. In five years a total of 11 deaths. The average age was 44 years and the average duration was 4.2 years. According to their deaths