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有许多迹象表明,类风湿性关节炎是一种自身免疫性疾病。类风湿性关节炎病人血清中存在着多种自身抗体,不仅有类风湿因子,还有抗核抗体、抗淋巴细胞抗体、抗粒细胞抗体、抗胶原抗体等。病人滑膜液中存在着大量的免疫球蛋白聚合体,补体水平下降。早期病人的病灶部位有明显的血管炎现象。类风湿关节炎与组织相容性抗原HLA—D型有关联。HLA—D抗原可能是特异性免疫应答基因(Ir)的产物。胸导管引流排减淋巴细
There are many indications that rheumatoid arthritis is an autoimmune disease. Rheumatoid arthritis patients in the presence of a variety of autoantibodies, not only rheumatoid factor, but also anti-nuclear antibodies, anti-lymphocyte antibodies, anti-granulocyte antibodies, anti-collagen antibodies. Patients with synovial fluid in the presence of a large number of immunoglobulin aggregates, complement levels decreased. Early lesions of patients with obvious vasculitis phenomenon. Rheumatoid arthritis is associated with HLA-D histocompatibility antigens. The HLA-D antigen may be the product of a specific immune response gene (Ir). Thoracic drainage catheter drainage row thinner