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本文观察几种常用的活血化瘀及免疫抑制药物对Masugi肾炎的疗效,以便筛选治疗急性肾炎的有效药物。 实验步骤 选择体重2kg的白色家兔,在动物室饲养2周,无病态,且经尿常规及肾功能检查证实无肾脏损害。实验时按照本组改良的Vassalli方法制成抗肾抗体肾炎模型,即Masugi肾炎。治疗前各项检查在注射抗肾抗体后7~10日,即蛋白尿高峰期进行,治疗
This article observed several commonly used blood circulation and immunosuppressive drugs on Masugi nephritis curative effect in order to screen effective drugs for the treatment of acute nephritis. Experimental Procedures White rabbits weighing 2 kg were housed for 2 weeks in an animal room and were free of pathological conditions and confirmed as having no kidney damage by urinalysis and renal function tests. Experiments in accordance with the improved Vassalli method of this group made anti-renal antibody nephritis model, Masugi nephritis. Before the treatment of various tests in the injection of anti-renal antibodies after 7 to 10, the peak proteinuria, treatment