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AIDS可并发Kaposi氏肉瘤、肺囊虫肺炎、播散性鸟型分枝杆菌菌血症、肛周慢性单纯疱疹等,而并发进行性多灶性脑白质病(PML)的危险性目前已为人们所注意。作者报道2例AIDS并发PML,并讨论其诊断、预后及治疗。例1:同性恋男性,32岁,右利手。进行性左手笨绌、无力7周入院,并有嗜睡、健忘、厌食、体重减轻、寒战、发热和干咳。入院前17天作胸部X线及支气管活检,诊断为卡氏肺囊虫肺炎,给予SMZ和TMP治疗10天。因血培养有真菌生长而接受两性霉素治疗6周。既往曾患甲型、乙型肝炎,因三期梅毒而注射青霉素G钾4周,牛皮癣病史多年,滥用大黄、烟草,偶服苯基丙胺和巴比妥酸
AIDS can be complicated by Kaposi’s sarcoma, Pneumocystis pneumonia, disseminated Mycobacterium avium bacteremia, perianal chronic herpes simplex, etc., and the risk of concurrent progressive multifocal leukoencephalopathy (PML) is now People pay attention. The authors report 2 cases of AIDS complicated with PML, and discuss its diagnosis, prognosis and treatment. Example 1: Homosexual male, 32, right hand. Progressive left-handed stupid, unable to hospital for 7 weeks with drowsiness, forgetfulness, anorexia, weight loss, chills, fever and dry cough. 17 days before admission for chest X-ray and bronchial biopsy, diagnosis of Pneumocystis carinii pneumonia, given SMZ and TMP for 10 days. Amphotericin treatment for 6 weeks due to fungal growth in blood cultures. Previously suffered from hepatitis A, penicillin G potassium for 3 weeks due to tertiary syphilis, history of psoriasis for many years, abuse of rhubarb, tobacco, even phenylpropylamine and barbituric acid