目的　更好地认识癌变息肉的临床特点 ,找出与癌变息肉相关的因素 ,为临床初步判断息肉的性质提供依据。方法　回顾整理连续 4年内资料完整可用的结肠息肉病例 ,分析性别、年龄、息肉部位、数目、是否有蒂、黏膜情况、是否分叶、病理类型、息肉大小、不典型增生程度等因素。结果　单因素分析显示癌变与未癌变息肉在大小、黏膜情况、不典型增生程度、病理类型、是否分叶状等因素方面的差别具有统计学意义。逐步Logistic分析显示与癌变息肉独立相关的因素包括息肉大小、不典型增生程度、黏膜情况、是否有蒂及病理类型。结论　息肉越大、病理为腺瘤、不典型增生程度越重、黏膜有糜烂甚至溃疡、亚蒂或无蒂是与癌变息肉独立相关的因素 ,以上因素符合的越多则该息肉为恶性的可能性越大 Objective To better understand the clinical features of cancerous polyps, identify the factors associated with cancerous polyps, and provide a basis for the preliminary judgment of the nature of polyps. Methods The cases of colonic polyps with complete and available data for 4 consecutive years were reviewed and analyzed. Factors such as sex, age, number and location of polyps, whether pedunculated, mucosa, lobulated, pathological type, polyp size and dysplasia were analyzed. Results Univariate analysis showed that the difference between cancerous and non-cancerous polyps in size, mucosa, atypical hyperplasia, pathological type, lobulated or not was statistically significant. Stepwise Logistic analysis revealed that the factors independently associated with cancerous polyps included polyp size, atypical hyperplasia, mucosal conditions, pedunculated and pathologic types. Conclusion The larger the polyp, the pathological adenoma, the more severe the atypical hyperplasia, the mucosal erosions and even the ulcer, the pedicel or the pedicle is an independent factor related to the cancerous polyps. The more the above factors are, the polyp may be malignant The more sex