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注射用炎琥宁是由穿心莲内酯与琥珀酸酐经半合成后得到的有着明确化学单体的中药西制产品[1],相对分子质量610.68,具有清热解毒作用,临床上常用于治疗上呼吸道感染、急慢性支气管炎、病毒性肺炎、婴幼儿急性上呼吸道感染等。近年来,随着炎琥宁在临床上的广泛应用,出现了一些配伍反应,为指导临床用药,本研究拟对炎琥宁注射液与4种输液进行配伍试验,考察其外观、p H值、不溶性微粒及含量变化,现报告如下。
Injection of mesylate is derived from andrographolide succinic anhydride semi-synthetic medicine obtained with a clear chemical monomer of Western products [1], the relative molecular mass of 610.68, with heat-clearing and detoxification, clinically used in the treatment of upper respiratory tract Infection, acute and chronic bronchitis, viral pneumonia, infantile acute upper respiratory tract infection. In recent years, with the widespread application of Yanhu Ning in clinical, there have been some compatibility reactions, in order to guide the clinical medication, this study intended to Yanhuoning injection and four kinds of infusion compatibility test to investigate the appearance, p H value , Insoluble particles and content changes, are as follows.