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应用石蜡切片免疫组织化学ＢＡ法回顾性观察了６８例大肠癌组织雌激素受体（ＥＲ）与孕激素受体（ＰＲ）的表达。结果大肠癌ＥＲ／ＰＲ阳性率为４５．６％和３８．３％，表明癌组织具有ＥＲ／ＰＲ依赖性。其阳性率与患者的年龄、组织学类型有关，年龄越大肿瘤分化程度越高，阳性率越高，与患者性别无关。认为ＥＲ／ＰＲ可作为判别肿瘤的恶性程度及选择内分泌治疗的指标。
The paraffin section immunohistochemical BA method was used to retrospectively observe the expression of estrogen receptor (ER) and progesterone receptor (PR) in 68 cases of colorectal cancer. Results The positive rates of ER/PR in colorectal cancer were 45.6% and 38.3%, indicating that the cancer tissue had ER/PR-dependence. The positive rate was related to the patient’s age and histological type. The older the higher the degree of tumor differentiation, the higher the positive rate and not related to the patient’s gender. It is considered that ER/PR can be used as an indicator for judging the malignancy of a tumor and selecting an endocrine therapy.