造血干细胞移植后 ,利用异基因供体外周血白细胞输注可增强移植物抗白血病反应 ,有利于进一步清除体内白血病微量残留病灶 ,从而使患者达到分子水平、细胞水平或临床缓解 ,有效地预防和治疗白血病的复发。本文就该疗法的机制、适应证、疗效、并发症、治疗方法及疗效监测等进行综述。 Hematopoietic stem cell transplantation, the use of allogeneic donor peripheral blood leukocyte infusion can enhance the graft anti-leukemia response is conducive to further clearance of micro-residual leftover lesions in vivo, so that patients reach molecular level, cell level or clinical remission, effectively prevent and Treatment of leukemia recurrence. This article reviews the mechanism of the therapy, indications, curative effects, complications, treatment methods and efficacy monitoring.