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相当多的肝细胞癌 (ＨＣＣ)患者有变异型肝脏雌激素受体 (ｖＥＲ)和野生型ＥＲ(ｗｔＥＲ) ,前者有较高的临床侵袭性和对三苯氧胺的不反应性 ,而甲地孕酮则会有较好的作用。本文报道一个随机试验来确定用甲地孕酮治疗ｖＥＲ的ＨＣＣ患?
A significant number of patients with hepatocellular carcinoma (HCC) have variant hepatic estrogen receptor (vER) and wild-type ER (wtER), the former with higher clinical aggressiveness and non-responsiveness to tamoxifen, while megestrol It will have a better effect. This article reports a randomized trial to determine if HME is treated with megestrol for vER.