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目的:观察健脾益肺方联合沙美特罗氟替卡松干粉吸入剂治疗小儿哮喘缓解期的效果。方法:纳入90例哮喘缓解期脾肺气虚证患儿,将患儿随机分为2组各45例,对照组给予沙美特罗氟替卡松干粉吸入剂治疗,观察组在对照组基础上给予健脾益肺方治疗,评估2组的临床疗效、中医症状评分,并检测免疫球蛋白。结果:观察组治疗总有效率为95.56%,高于对照组的77.78%,差异有统计学意义(P<0.05)。治疗后,2组咳嗽程度、咳嗽次数、喷嚏、咯痰评分均低于治疗前,差异均有统计学意义(P<0.05)。观察组各项评分均低于对照组,差异均有统计学意义(P<0.05)。2组IgA、IgM水平均较治疗前上升,差异均有统计学意义(P<0.05);观察组IgA、IgM水平均高于对照组,差异均有统计学意义(P<0.05)。结论:健脾益肺方联合沙美特罗氟替卡松干粉吸入剂治疗小儿哮喘缓解期安全有效,不仅能够有效改善咯痰、咳嗽等症状,还能够改善机体的免疫功能,提高临床疗效。
Objective: To observe the effect of Jianpi Yifei Fang combined with salmeterol fluticasone dry powder inhalation in the treatment of pediatric asthma remission. Methods: Ninety children with spleen-qi-deficiency syndrome were included in the remission stage of asthma. The children were randomly divided into two groups (n = 45). The control group was given salmeterol fluticasone dry powder inhalation. The observation group was given spleen- Pulmonary treatment, to assess the clinical efficacy of two groups, TCM symptom score, and detection of immunoglobulin. Results: The total effective rate of the observation group was 95.56%, which was higher than that of the control group (77.78%), the difference was statistically significant (P <0.05). After treatment, the scores of cough, cough, sneeze and expectoration were all lower than those before treatment (P <0.05). The score of the observation group was lower than that of the control group, the difference was statistically significant (P <0.05). The levels of IgA and IgM in both groups were significantly higher than those before treatment (P <0.05). The levels of IgA and IgM in the observation group were significantly higher than those in the control group (P <0.05). Conclusion: Jianpi Yifei Recipe combined with salmeterol fluticasone dry powder inhalation is safe and effective in remission of childhood asthma, which can not only effectively improve the symptoms such as expectoration and cough, but also improve the immune function and improve the clinical curative effect.