全身性硬皮病是一种结缔组织发生硬化的全身性疾病。患者除皮肤变硬外,关节、肌腱、内脏等也发生硬化,以致颜面变形、关节损伤、活动受限、摄食困难以及其他内脏功能障碍等等,严重者丧失劳动能力,生活不能自理,而且常因心、肾等脏器受损而导致死亡。我们 Systemic scleroderma is a systemic disease that hardens connective tissue. Patients in addition to skin hardening, the joints, tendons, viscera and other hardening also occurs, resulting in facial deformity, joint damage, limited mobility, feeding difficulties and other visceral dysfunction, etc., serious loss of working ability, life can not take care of themselves, and often Due to heart, kidney and other organ damage caused by death. we