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远志超声气雾液在临床上能有效地增加肺癌病人痰液中癌细胞的检出率。近年来,我院用远志的10%水溶液,以超声气雾后经口腔给药用于肺癌病人的诊断,经临床应用表明,能有效地增加痰液中癌细胞检出的阳性率,对肺癌的早期诊断有积极的意义。远志为常用祛痰中药,能增加支气管分泌及粘膜上皮纤毛运动,主要有效成分为远志皂甙。目前我院使用的远志超声气雾液,是将远志水煎三次,合并水煎液,浓缩后经乙醇二次沉淀,一次明胶沉淀后得到的澄清液。为简化制备方法,保持制剂质量的稳定,作者探索用不同方法制备并比较其质量,结果报道如下。
Polygala ultrasonic aerosol can effectively increase the detection rate of cancer cells in sputum of lung cancer patients. In recent years, our hospital used Polygalaceae 10% aqueous solution, after ultrasonic aerosol after oral administration for the diagnosis of lung cancer patients, clinical application shows that can increase the positive rate of cancer cells in sputum, lung cancer The early diagnosis has positive significance. Polygala is a commonly used traditional Chinese medicine, which can increase bronchial secretion and mucociliary movement. The main active ingredient is Polygala saponin. At present, Polygala Ultrasonic Aerosol Fluid used in our hospital is a clear solution obtained by boiling water of Polygala tenuifolia three times, combining water decoction, concentrating, secondary precipitation of ethanol, and one-time gelatin precipitation. In order to simplify the preparation method and maintain the stability of the preparation quality, the authors explored using different methods to prepare and compare their quality. The results are reported below.