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一、序言经皮的肾脏活检方法发表以来,肾脏病的组织学研究深入了一步,Coons等通过应用荧光抗体法,了解了各种免疫球蛋白、纤维蛋白样物质、补体、引起肾炎的抗原在肾组织的沉着形式和程度,应用电子显微镜酶抗体法、铁蛋白抗体法等,进行了免疫组织学的研究。目前,认为多数肾小球肾炎是通过免疫学机制产生的。在血中产生了可溶性免疫复体,沉积在肾小球成为其主要原因。
I. Introduction Since the publication of the percutaneous kidney biopsy method, the histological study of kidney disease has taken a step further. Coons et al. Used various fluorescent antibody methods to understand the immunoglobulin, fibrin-like substances, complement, and the antigens causing nephritis The form and degree of renal tissue deposition, the application of electron microscopy enzyme antibody method, ferritin antibody method, the study of immunohistochemistry. Currently, most glomerulonephritis is thought to be produced by immunological mechanisms. Soluble immunocomplexes are produced in the blood and deposit in the glomerulus becomes the main cause.