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目的分析换血治疗对重度高胆红素血症新生儿疗效。方法 52例重度高胆红素血症新生儿采用换血治疗(全自动动静脉同步换血法),通过换血前、中、后血糖、急诊八项、胆红素各项指标变化,分析换血治疗的疗效。结果患儿换血前与换血中总胆红素、间接胆红素、血钾、血钠、血氯、总蛋白、血糖比较,差异有统计学意义(P<0.05);血钙、尿素、肌酐比较差异无统计学意义(P>0.05)。换血前总胆红素、间接胆红素、总蛋白[(505.00±81.46)μmol/L、(473.71±72.87)μmol/L、(51.95±4.26)g/L]与换血后[(166.79±58.91)μmol/L、(154.86±58.13)μmol/L、(46.34±4.51)g/L]比较,差异有统计学意义(P<0.05);血钾、血钠、血氯、血钙、尿素、肌酐、血糖比较差异无统计学意义(P>0.05)。患儿均治愈出院。结论换血治疗对新生儿重度高胆红素血症疗效显著,安全可靠,见效快,预后好。
Objective To analyze the effect of blood transfusion on neonates with severe hyperbilirubinemia. Methods Fifty-two neonates with severe hyperbilirubinemia were treated with transfusions (automatic synchronized arterial-venous transfusion). The changes of various indexes of bilirubin before, during, after and after blood transfusion were analyzed. Efficacy. Results There was significant difference in total bilirubin, indirect bilirubin, serum potassium, serum sodium, blood chloride, total protein and blood glucose before blood transfusion and blood exchange in children (P <0.05), while blood calcium, urea and creatinine The difference was not statistically significant (P> 0.05). The levels of total bilirubin, indirect bilirubin, total protein [(505.00 ± 81.46) μmol / L, (473.71 ± 72.87) μmol / L and (51.95 ± 4.26) g / L] (P <0.05). There was significant difference between the two groups (P <0.05); serum potassium, blood sodium, serum calcium, urea, Creatinine, blood glucose was no significant difference (P> 0.05). Children were cured and discharged. Conclusion Transfusion therapy has significant effect on neonatal severe hyperbilirubinemia, which is safe and reliable, quick and good prognosis.