要本文应用生物学测定法检测了肝癌、胃癌、大肠癌、喉癌、乳腺癌外周血Ｔ淋巴细胞丝裂原反应性和血浆ＩＬ－２、ＩＬ－６活性及ＩＬ－２受体的表达。结果表明：各组癌症患者Ｔ淋巴细胞丝裂原反应性和血浆ＩＬ－２、ＩＬ－６活性均显著低于对照组，而ＩＬ－２Ｒ表达却显著高于对照组。各组癌症之间上述各项指标比较均无明显差异。结果提示，癌症患者外周血Ｔ细胞功能被严重抑制，ＩＬ－２、ＩＬ－６和ＩＬ－２Ｒ可能在该病的发病机制中起一定作用 To determine the mitogen responsiveness of peripheral blood T lymphocytes, plasma IL-2, IL-6 activity and IL-2 receptor expression in liver cancer, gastric cancer, colorectal cancer, laryngeal cancer, and breast cancer by biological assays. The results showed that the mitogen reactivity of T lymphocytes and plasma IL-2 and IL-6 activity were significantly lower in the cancer patients than in the control group, while the expression of IL-2R was significantly higher in the cancer patients than in the control group. There was no significant difference in the above indicators between the groups of cancers. The results suggest that peripheral blood T cell function is severely inhibited in cancer patients, and IL-2, IL-6 and IL-2R may play a role in the pathogenesis of this disease.