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目的了解呼吸道感染儿童中肺炎支原体(MP)感染情况,为临床早期诊断和治疗提供可靠依据。方法采用胶体金法检测2 428例患儿血清中MP-IgM抗体,同时做其他相关实验室检查。结果 2 428例儿童的血清标本中检出MP-IgM抗体阳性535例,阳性率为22.03%,其中男童阳性率为21.05%,女童阳性率为23.19%,男女患儿之间阳性率差异无统计学意义(χ~2=3.84,P>0.05)。四季均可检出呼吸道感染患儿MP-IgM抗体,其中冬季阳性率最高(28.07%),秋季次之(24.92%)。随着年龄的增长阳性率呈逐渐上升趋势,7岁~14岁儿童阳性率最高(36.96%)。结论胶体金法检测血清MP-IgM抗体操作简单,具有较高的敏感性和特异性,与血常规等联合检测有利于MP的早期诊断,本地区学龄前及学龄儿童为高危人群,临床应加强对MP的监控。
Objective To understand the infection of Mycoplasma pneumoniae (MP) in children with respiratory tract infection and provide a reliable basis for early clinical diagnosis and treatment. Methods The serum MP-IgM antibodies in 2 428 children were assayed by colloidal gold method and other related laboratory tests were performed at the same time. Results There were 535 positive cases of MP-IgM antibodies in 2 428 children, the positive rate was 22.03%, of which the positive rate was 21.05% in boys and 23.19% in girls, the difference between male and female children was no Statistical significance (χ ~ 2 = 3.84, P> 0.05). MP-IgM antibodies were detected in children with respiratory tract infections in all seasons, with the highest positive rate in winter (28.07%) and the second highest rate (24.92%) in autumn. The positive rate showed a gradual upward trend with age, the highest positive rate (36.96%) in children aged 7 to 14 years. Conclusion Colloidal gold assay of serum MP-IgM antibody is simple and has high sensitivity and specificity. Combined with blood tests, it is good for the early diagnosis of MP. The preschool and school-age children in this area are at high risk, and should be clinically strengthened Monitor the MP.