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目的:评价静脉溶栓联合血管内治疗与单纯静脉溶栓治疗急性后循环脑梗死的疗效。方法:回顾性分析24例经动静脉联合治疗(联合组)和22例经静脉溶栓(静脉组)的病例资料,分析两组的血管再通、临床预后及并发症情况。结果:联合组和静脉组溶栓后闭塞血管再通率分别为70.8%和18.2%(P<0.05);症状性颅内出血率分为12.5%和9.1%,死亡率分别为8.3%和9.1%,差异无统计学意义(P>0.05);术后14 d的美国国立卫生院卒中量表(NIHSS)评分、3个月后Rankin量表(m RS)评分联合组明显优于静脉组(P<0.01)。结论:相对于静脉溶栓,动静脉联合治疗血管再通率、疗效可能更佳,但结果仍有待于大样本、双盲、对照试验证实。
Objective: To evaluate the efficacy of intravenous thrombolysis combined with endovascular treatment and intravenous thrombolysis in the treatment of acute posterior circulation cerebral infarction. Methods: A retrospective analysis of 24 cases of combined arteriovenous (combination group) and 22 cases of intravenous thrombolysis (venous group) of the case data, the two groups of recanalization, clinical prognosis and complications. Results: The recanalization rate of occlusion after thrombolytic therapy was 70.8% and 18.2% respectively in the combination group and the venous group (P <0.05). The rates of symptomatic intracranial hemorrhage were 12.5% and 9.1% respectively, the mortality rates were 8.3% and 9.1% (P> 0.05). The National Institutes of Health Stroke Scale (NIHSS) score and the Rankin Scale (m RS) score after 3 months in the combined group were significantly better than those in the intravenous group <0.01). Conclusion: Compared with intravenous thrombolysis and arterio-venous treatment, the curative effect may be better, but the results still need to be confirmed by large sample, double-blind and controlled trial.