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应激性溃疡是危重病人常见的一种急性胃粘膜病变,发病机制未明。本实验通过对应激状态下家兔血清TXA2水平变化及胃粘膜及粘膜下层微循环变化的观察,认识到血清TXA2水平的急剧上升及其所导致的胃组织微循环障碍是家兔应激性溃疡发生、发展的重要发病机制之一。
Stress ulcer is a common acute gastric mucosal lesions in critically ill patients, the pathogenesis is unknown. This experiment through the rabbit’s serum TXA2 levels under stress and microcosmic changes of gastric mucosa and submucosa observed that the serum TXA2 levels rose sharply and the resulting gastric microcirculation disorder is a stress ulcer in rabbits Occurrence and development of one of the important pathogenesis.