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目的:观察复方苦参注射液联合氟比洛芬酯脂微球注射液治疗中晚期癌痛的临床疗效。方法:将70例中重度癌痛患者随机分为联合治疗组和对照组各35例。联合治疗组予复方苦参注射液联合氟比洛芬酯脂微球注射液治疗,对照组仅予氟比洛芬酯脂微球注射液治疗。结果:联合治疗组疼痛缓解率、不良反应发生率均优于对照组(P<0.05)。结论:复方苦参注射液联合氟比洛芬酯脂微球注射液能有效缓解中重度癌痛,明显改善患者的生活质量,不良反应较单用氟比洛芬酯脂微球注射液减少。
Objective: To observe the clinical curative effect of Fufang Kushen injection combined with flurbiprofen axetil microsphere injection in the treatment of middle-late stage cancer pain. Methods: Seventy patients with moderate-to-severe cancer pain were randomly divided into three groups: 35 cases in combination therapy group and control group. The combined treatment group to Compound Kushen injection combined with flurbiprofen ester lipid microsphere injection treatment, the control group only flurbiprofen ester lipid microsphere injection treatment. Results: The pain relief rate and adverse reaction rate in the combined treatment group were better than those in the control group (P <0.05). Conclusion: Compound Kushen injection combined with flurbiprofen ester lipid microsphere injection can effectively relieve moderate and severe cancer pain, and significantly improve the quality of life of patients. The adverse reaction is less than that of flurbiprofen ester lipid microsphere injection alone.