透明质酸 (Hyaluronicacid ,HA)是一种天然的高分子直链黏多糖 ,广泛存在于动物和人体组织及细胞外基质中 ,商品HA一般为其钠盐。HA在机体内具有重要的生理功能 ,被认为是一种填充空间、稳定结构、涂层细胞和保护细胞的多糖。目前 ,临床上HA已广泛应用于眼科、耳鼻喉科、骨科及普外科等 ,并取得了令人满意的效果。文章主要阐述HA抗氧化作用的临床应用研究现状 Hyaluronic acid (HA) is a natural macromolecule linear mucopolysaccharide, widely found in animal and human tissues and the extracellular matrix. The HA of a commercial product is generally its sodium salt. HA has important physiological functions in the body and is thought to be a kind of polysaccharide that fills the space, stabilizes the structure, coats the cells, and protects the cells. At present, clinical HA has been widely used in ophthalmology, otolaryngology, orthopedics and general surgery, and achieved satisfactory results. The article mainly expounds the clinical application and research status of anti-oxidation of HA