在眼科临床上,全身或局部给药后,药物能否(或有多少)达到眼组织的作用部位,从而产生治疗效果,是眼科医生十分关心的问题。药物能否达到眼组织作用部位多半取决于它穿透眼部各种生物膜的能力。因此,了解生物膜的结构以及药物如何通过生物膜的一般规律,将有助于我们进一步研究药物对眼的渗透性。 In ophthalmology, it is a matter of concern for ophthalmologists to consider whether the drug can (or how much) reach the site of ocular tissue after systemic or topical administration, resulting in a therapeutic effect. The ability of a drug to reach the site of ocular tissue depends mostly on its ability to penetrate various biofilms in the eye. Therefore, understanding the structure of the biofilm and the general rules of how the drug passes through the biofilm will help us to further study the drug’s permeability to the eye.