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目的了解接受血管内支架植入术(ESI)的缺血性脑血管病(ICVD)患者术后对抗血小板聚集药物治疗(APT)的依从性及其影响因素。方法收集138例头颈部血管支架术后1年以上的患者,采用改良Morisky量表评估患者对APT的依从性及可能的影响因素,以得分>7.50分定义为服药依从性好,≤7.50分为服药依从性差;用多因素Logistic回归方法分析影响患者服药依从性的因素。结果 138例行头颈部血管支架植入术的患者中术后76例(55.07%)APT依从性良好,62例(44.93%)APT依从性差。服药依从性差主要与初中文化程度、无医疗保险、吸烟、不了解抗血小板聚集药需要的时间等相关。结论行ESI的ICVD患者的APT依从性亟待提高。对文化程度偏低、无医疗保险、吸烟的患者,应加强教育,反复告知需要APT的时间及服药的重要性,以减少缺血性脑血管病的复发。
Objective To investigate the compliance of postoperative antiplatelet drug therapy (APT) and its influencing factors in patients with ischemic cerebrovascular disease (ICVD) undergoing endovascular stent grafting (ESI). Methods A total of 138 patients with head and neck vascular stenting who were followed up for more than one year were enrolled in this study. The patients’ compliance with APT and the possible influencing factors were evaluated by a modified Morisky scale. The score> 7.50 was defined as good compliance and ≤7.50 Poor medication compliance; using multivariate logistic regression analysis of factors affecting the patient’s medication compliance. Results Among the 138 patients undergoing head and neck stenting, 76 (55.07%) had good compliance with APT and 62 (44.93%) had poor compliance with APT. Compliance with poor medication mainly with junior high school education, no medical insurance, smoking, do not understand the anti-platelet aggregation drug needs such as time-related. Conclusions The APT compliance of patients undergoing ICVD with ESI should be improved urgently. Patients with low education level, no medical insurance and smoking should be educated to repeatedly inform them of the time required for taking APT and the importance of taking medicine so as to reduce the recurrence of ischemic cerebrovascular disease.