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目的了解石家庄市中老年代谢综合征(MS)人群糖化血红蛋白(HbA1c)水平及糖代谢特点,了解不同糖代谢及HbA1c水平下MS患病情况。方法分层随机抽样选择石家庄市9个社区,居住5年以上,年龄≥45岁的社区居民,进行横断面流行病学问卷调查和体格检查,检测空腹血糖(FPG)、HbA1c、血脂及口服糖耐量试验。据1999年WHO糖尿病诊断标准和2005年IDF代谢综合征全球共识定义诊断。以HbA1c及糖代谢状态分成不同亚组,并进行统计学分析。结果石家庄市中老年人群MS患病率为21.2%,女性为14.8%,男性为6.4%(P<0.05);65岁以上和65岁以下人群分别为24.8%和19.7%(P<0.01)。HbA1c以6.5%为切点MS患病率分别为14.1%和59.7%(P<0.01)。其中除HbA1c<5.0%与HbA1c介于5.0%~6.0%时各组间MS患病率无差异外,HbA1c<6.5%时各分层之间及其与HbA1c≥6.5%时各分层间MS患病率两两不同。NGT、DM之间及其与IFG、IGT、IFG+IGT间,MS患病率两两不同。年龄、性别、糖尿病家族史、喜食甜食、BMI、WHR、TG、HDL-C、SBP、DBP、FPG、2h-PG、HbA1c为MS高发的主要危险因素。结论石家庄市MS患病率较高,HbA1c水平监控、糖代谢状态筛查,有助于MS的诊断及防控。
Objective To understand the level of glycated hemoglobin (HbA1c) and the characteristics of glucose metabolism in the elderly with metabolic syndrome (MS) in Shijiazhuang and to understand the prevalence of MS under different glucose metabolism and HbA1c levels. Methods Stratified random sampling was conducted in 9 communities in Shijiazhuang, with more than 5 years of living and ≥45 years of age. Cross-sectional epidemiological questionnaires and physical examinations were conducted to detect fasting blood glucose (FPG), HbA1c, lipids and oral glucose Endurance test. According to 1999 WHO diagnostic criteria for diabetes and IDF metabolic syndrome in 2005 the definition of a global consensus diagnosis. HbA1c and glucose metabolism into different subgroups, and statistical analysis. Results The prevalence of MS was 21.2% in middle-aged and elderly people in Shijiazhuang City, 14.8% in women and 6.4% in men (P <0.05). The prevalence of MS was 65.8% and 19.7% respectively in those over 65 years old and 19.7% (P <0.01). HbA1c with 6.5% cut point MS prevalence rates were 14.1% and 59.7% (P <0.01). There was no difference in the prevalence of MS among the groups except HbA1c <5.0% and HbA1c between 5.0% and 6.0%, between stratification of HbA1c <6.5% and between stratified MSs with HbA1c> 6.5% Prevalence varies between two. The prevalence of MS differs between NGT, DM and between IFG, IGT, IFG + IGT and MS. The main risk factors for MS were age, sex, family history of diabetes, sweet food, BMI, WHR, TG, HDL-C, SBP, DBP, FPG, 2h-PG and HbA1c. Conclusion The prevalence of MS in Shijiazhuang is high, the level of HbA1c is monitored, and the status of glucose metabolism is screened, which is helpful for the diagnosis and prevention of MS.