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慢性粒细胞白血病(慢粒)急红变少见,并自发性脾破裂更为罕见,现将我院1例报告如下;1 病例介绍 患者,男,63岁,因乏力腹胀2个月,于1986年11月22日入院.查体;一般情况良好.脾助下4cm,WBC34.6×10~9/L,Sg0.58,st0.09,中晚幼粒0.06,E 0.03,B 0.05,Hb 128g/L,BPC189×10~9/L,骨髓增生极度活跃,粒:红为12.3:1,原十早幼粒0、045,中晚幼粒0.51,杆状及分叶核0.245,E 0.025,B 0.044,早幼红0.05,中晚幼红0.06.诊断慢粒.服马利兰牌回缩,血象正常出院,未规律服马利兰症状复发,又于1988及1989年两次住院,用羟基脲(HU)及6—疏鸟嘌呤(6-TG)治疗血象接近正常,症状缓解出院.1990年2月第4次住院,脾助下7cm,WBC20.5×10~9/L,Hb102g/L,BPC89×10~9/L ,骨髓增生明显活跃,粒:红为3.66:1,早幼粒0.035,中晚幼粒0.345,杆状及分叶核0.305,E 0.04,В0.03.原红0.01,早幼红0.015,中晚幼红0.18.予
Chronic myelogenous leukemia (Chr) is an acute redness rarer, and spontaneous splenic rupture is even more rare. One case in our hospital is now reported as follows; 1 Case presentation of patients, male, 63 years old, due to fatigue, abdominal distension for 2 months, in 1986 On November 22, he was admitted to the hospital. Physical examination; generally good condition. Spleen-assisted 4 cm, WBC 34.6×10~9/L, Sg 0.58, st 0.09, middle and late grain 0.06, E 0.03, B 0.05, Hb 128g/L, BPC189×10~9/L, bone marrow hyperplasia extremely active, grain: red 12.3:1, original ten early-mature 0, 045, middle-late and late young 0.51, rod and nucleus 0.245, E 0.025 , B 0.044, early juvenile red 0.05, mid-late juvenile red 0.06. Diagnosis of chronic tablets. Take Maliland brand retraction, normal blood discharge, no regular relapse of symptoms of Malilan, and two hospitalizations in 1988 and 1989, with hydroxyurea ( HU) and 6- thioguanine (6-TG) were nearly normal in the treatment of hemogram, and the symptoms were relieved to discharge. In the fourth hospital in February 1990, the spleen assisted 7cm, WBC20.5×10~9/L, Hb102g/L, BPC89×10~9/L, myeloproliferation was apparently active. Granules: red was 3.66:1, early pronucleus 0.035, middle-late granule 0.345, rod and nucleus 0.305, E 0.04, В0.03. , early young and red 0.015, medium and late young red 0.18.