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IgA-肾小球肾炎(简称IgA-肾炎)在我们的病例中是最常见的一种肾炎,发生率占20%。与文献的报告相反,本病的预后是不良的。作者观察的50例中,17例于4～96个月的发展为肾功能不全,其中3例做了透析治疗。17例中的11例于确诊时肾功能仍属正常,5例有恶性高血压。断定非良性过程者常为男性患者,蛋白尿,高血压,年龄在30岁以上,肾脏在组织学上呈肾小球硬化,肾小管萎缩,肾间质纤维化和血管损害。血清IgA值和循环IgA复合物的增加
IgA-glomerulonephritis (IgA-nephritis) is the most common type of nephritis in our case, accounting for 20% of all cases. Contrary to the literature report, the prognosis of this disease is poor. Of the 50 observed cases, 17 developed renal insufficiency from 4 to 96 months, of whom 3 were dialysised. Eleven of the 17 patients remained normal with renal function at the time of diagnosis and 5 had malignant hypertension. To determine the non-benign process is often male patients, proteinuria, hypertension, age over 30 years of age, kidney showed histologically glomerular sclerosis, renal tubular atrophy, interstitial fibrosis and vascular damage. Serum IgA levels and circulating IgA complex increase