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最近以来,由于外科治疗技术的进步,特别是加强监护病房(ICU)的建立,使得一些创伤病人能渡过单一器官衰竭阶段而存活下来。但是在随后的病程中却出现了多器官衰竭(Multiple organ failure,MOF)这一新问题。器官衰竭的序列是:呼吸衰竭、心力衰竭、肝功能衰竭、肾功能衰竭、免疫防御机能衰竭等。多器官衰竭的预后差,病死率高达50～95％,已经成为危重病人救治工作中的一大障碍。 MOF的诱因是复杂的,例如严重创伤、感染、失血、休克、大量输血、手术错误等,其中以休克和感染最为常见。第一,休克;Faist等报道,79％的MOF病人入院
Recently, due to advances in surgical techniques, especially the intensive care unit (ICU), some trauma patients have survived single organ failure. However, in the subsequent course of the disease, a new problem of multiple organ failure (MOF) appeared. The sequence of organ failure is: respiratory failure, heart failure, liver failure, renal failure, immune defense failure and so on. The prognosis of multiple organ failure is poor, the mortality rate as high as 50 to 95%, has become a major obstacle in the treatment of critically ill patients. MOF incentives are complex, such as severe trauma, infection, blood loss, shock, a large number of blood transfusions, surgical errors, of which the most common shock and infection. First, shock; Faist et al reported that 79% of patients admitted to the MOF