Of Monkeys and Men: New Insights into Using Chinese Rhesus Macaque as a Viable Model of Human Aging

来源 :Bulletin of the Chinese Academy of Sciences | 被引量 : 0次 | 上传用户:BENLAOQIAN
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Of all human conditions,aging and death are perhaps the most universal.Unfortunately death among elderly populations is often a drawn out and painful affair,as advanced age is accompanied by marked rises in morbidity and mortality due to infectious diseases.Precisely why this is the case has been subject to a great deal of speculation,but one commonly held explanation is referred to as immunosenescence,where the human body undergoes a remodeling of both innate and adaptive immune responses,and some functions are enhanced while others diminished.Both responses are key to the human immune systems,which fights off outside Of all human conditions, aging and death are perhaps the most universal. Unfortunately death among elderly populations is often a drawn out and painful affair, as advanced age is accompanied by marked rises in morbidity and mortality due to infectious diseases.Precisely why this is the case has been subject to a great deal of speculation, but one of held held explanation is referred to as immunosenescence, where the human body undergoes a remodeling of both innate and adaptive immune responses, and some functions are enhanced while others diminished.Both responses are key to the human immune systems, which fights off outside
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