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本文对130例重症Graves’甲亢患者采用锂盐、糖皮质激素、131碘及β受体阻滞剂等综合性治疗,取得了良好的效果,现报告如下。1资料和方法1.1临床资料重症甲亢患者130例,男41例,女89例,年龄8-65岁,平均年龄36.4岁,病程1个月～20年,平均2.6年。患者均有明显的甲亢症状和体征,甲状腺不同程度地弥漫性肿大,心率≥110次/min,甲状腺激素及甲状腺吸131碘率异常增高。大部分患者不能正常从事工作和学习。75例(57.7%)患者伴有明显的突眼症,17例(13.1%)伴有甲亢性心脏病,9例(6.9%)伴有周期性麻痹。94例(72.3%)患者经抗甲状腺药物治疗效果不佳。1.2治疗方法患者停服抗甲状腺药1周,服131碘治疗前、
The 130 cases of Graves’ hyperthyroidism patients with lithium, glucocorticoid, 131I and β-blockers and other comprehensive treatment, and achieved good results, are as follows. 1 Materials and Methods 1.1 Clinical data 130 patients with severe hyperthyroidism, 41 males and 89 females, aged 8-65 years, mean age 36.4 years, duration of 1 month to 20 years, an average of 2.6 years. Patients had obvious symptoms and signs of hyperthyroidism, varying degrees of diffuse thyroid enlargement, heart rate ≥ 110 beats / min, thyroid hormone and thyroid uptake of iodine 131 increased abnormally. Most patients can not work and study properly. 75 cases (57.7%) had obvious exophthalmos, 17 (13.1%) had hyperthyroid heart disease, and 9 (6.9%) had periodic paralysis. Ninety-four patients (72.3%) were ineffective with antithyroid drugs. 1.2 treatment of patients taking anti-thyroid drugs 1 week, taking 131 iodine before treatment,