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本文运用单克隆抗体Ｄ＿７结合另外一些抗细胞表面抗原的单克隆抗体，通过流式细胞计研究了Ｌｙ－６基因产物之一──Ｌｙ－６Ａ／Ｅ抗原分子在骨髓细胞上的表达，发现１８．０３％的Ｂ＿（２２０）＋细胞表达ＬＹ－６Ａ／Ｅ分子。表达Ｌｙ－６Ａ／Ｅ的Ｔ淋巴细胞（Ｔｈｙ－１￣＋）为２６．２５％。另外．还有少量的粒细胞（２．６９％）和巨噬细胞（２．９４％）表达Ｌｙ－６Ａ／Ｅ。表明Ｌｙ－６Ａ／Ｅ分子不是一种分化抗原，而是广泛存在于不同表型的细胞上。本文还发现骨髓Ｄ＿７＋Ｂ＿（２２０）－细胞群可能代表前Ｂ细胞的表型。
In this study, monoclonal antibody D_7 combined with other anti-cell surface antigen monoclonal antibody by flow cytometry Ly-6 gene product ─ ─ Ly-6A / E antigen in bone marrow cells, the expression of 18 .03% of B 220 cells expressed LY-6A / E molecules. T Lymphocytes (Thy-1 +) expressing Ly-6A / E were 26.25%. In addition. A small amount of granulocytes (2.69%) and macrophages (2.94%) expressed Ly-6A / E. It shows that Ly-6A / E is not a differentiated antigen, but exists widely in cells of different phenotypes. We also found that the myeloid D7 + B (220) - cell population may represent the phenotype of pre-B cells.