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目的探讨抗逆转录病毒(HAART)疗法与短程化疗方案同步治疗艾滋病病毒合并肺结核感染患者的临床疗效。方法对8例观察对象,采用AZT+DDI+NVP抗病毒方案、2H3R3Z3E3/4H3R3抗结核方案同步治疗。结果 8例患者中4例临床治愈,3例完成疗程,1例胸片示病灶吸收好转继续服药。治疗6个月、治疗9个月的CD4+T淋巴细胞计数较治疗前均有明显提高(P<0.05)。结论该抗病毒、抗结核双重治疗方案,可有效控制结核病,提高患者免疫力,切实可行。
Objective To investigate the clinical efficacy of anti-retroviral therapy (HAART) combined with short-course chemotherapy in the treatment of HIV-infected patients with tuberculosis. Methods 8 cases of observation object, using AZT + DDI + NVP antiviral program, 2H3R3Z3E3 / 4H3R3 anti-TB regimen simultaneously. Results Of the 8 patients, 4 were cured clinically, 3 completed the course of treatment, and 1 patient showed better absorption of the lesion and continued to take the medication. The counts of CD4 + T lymphocytes after 6 months of treatment and 9 months of treatment were significantly higher than those before treatment (P <0.05). Conclusion The dual anti-virus and anti-tuberculosis treatment regimen can effectively control tuberculosis and improve the immunity of patients, and is feasible.