关于感染猴疟原虫后是否出现血凝异常,意见不一。六十年代的研究认为凝血因子和血小板明显降低,肝素治疗有效;七十年代有人报告,因子Ⅴ、Ⅷ、Ⅹ暂时减少,纤维蛋白原和血小板增多,肝素对原虫出现时间、原虫密度和死亡时间均无影响。作者等以低温保存的虫种感染弥猴,作为种源猴。取其静脉血转种给10只猴,每猴约50万个原虫,等分成两组进行研究。接种后第3天见虫,第6天原虫密度平均为每万红细胞6,054,死1猴;第7天为7,750,全部死亡。观察项目有:血小板,血细胞容积,鱼 Opinions were raised on whether there was an abnormal blood coagulation after the infection of Plasmodium. In the 1960s, clotting factors and platelets were significantly reduced and heparin therapy was effective. In the 1970s it was reported that there was a temporary decrease in factors Ⅴ, Ⅷ and Ⅹ, fibrinogen and thrombocytopaenia, heparin production in protozoa, protozoal density and death time No effect. The authors infected the monkeys with cryopreserved worms as provenance monkeys. Take its venous blood transplanted to 10 monkeys, about 500,000 per monkey protozoan, equally divided into two groups to study. Insects were found on the third day after inoculation. On the sixth day, the average density of protozoa was 6,054 per million erythrocytes, 1 monkey died, and 7,750 died on the 7th day. Observation items are: platelets, hematocrit, fish