系统性硬皮病属临床少见病,有肾脏损害,引起急性肾衰者更属罕见。我们收治一例,报告如下。患者,女,54岁,1989年10月以来,渐出现颜面、手背、丰指麻木、发紫、硬肿,同年11月查尿蛋白~(+++),白细胞十,颗粒管型1～2/HP。入院时查体:BP20/15kpa,体重130kg,皮肤弥漫性硬肿,皱纹消失或明显减少,以颜面、手背、手指明显,呈 Systematic scleroderma is a clinical rare disease, kidney damage, acute renal failure caused by more rare. We treat one case, the report is as follows. Patients, female, 54 years old, since October 1989, gradually appeared face, back of the hand, Feng Zhi numbness, purple, sclerosis, the same year in November check urinary protein ~ (+++), leukocytes ten, 2 / HP. Admission examination: BP20 / 15kpa, weight 130kg, diffuse sclerous skin, wrinkles disappeared or significantly reduced to the face, back of the hand, fingers were significantly, was