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目的:观察小剂量氯胺酮、胃复安、阿托品联合应用,在人工流产术中的镇痛、镇静作用,了解其不良反应。方法:选取2005年1月～2005年10月在本院实施无痛人工流产术的患者150例,分为A、B、C3组,A组以1%氯胺酮、胃复安、阿托晶混合后静脉注射;B组术中宫颈多点注射2%利多卡因;C组2%利多卡因宫颈粘膜浸润麻醉。结果:镇痛、镇静效果及人工流产综合反应情况比较,A组与B和C两组间有显著性差异,P<0.01。术后发烧、感染情况比较B组与A组有显著性差异,P<0.05,A组与C组无差异P>0.05;出血情况A、B、C3组间无差异。结论:氯胺酮、胃复安、阿托品联合用于无痛人工流产术,镇痛效果佳,有效降低人工流产综合反应,不影响术中术后出血及感染情况,用药简单、安全可靠,值得推广应用。
OBJECTIVE: To observe the analgesic and sedation effects of low-dose ketamine, metoclopramide and atropine in abortion, and to understand its adverse reactions. Methods: A total of 150 patients with painless abortion in our hospital from January 2005 to October 2005 were selected and divided into groups A, B and C. The patients in group A were treated with 1% ketamine, metoclopramide, After intravenous injection, intraperitoneal injection of 2% lidocaine was performed in group B; cervical lidocaine 2% lidocaine in group C was anesthetized. Results: The analgesic, sedative effects and the incidence of induced abortion were significantly different between groups A and B and C (P <0.01). Postoperative fever, infection compared B group and A group had significant difference, P <0.05, A group and C group no difference P> 0.05; bleeding A, B, C3 no difference between groups. Conclusions: Ketamine, metoclopramide and atropine combined with painless artificial abortion have good analgesic effect, effectively reduce the comprehensive reaction of induced abortion, do not affect postoperative bleeding and infection during operation, and are simple, safe and reliable, which is worth popularizing and applying .