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目的:试验鼠细胞悬液和全胚细胞悬液对荷瘤小鼠的影响。方法:本试验用TA2系小鼠孕中期和孕末期胚肝细胞,悬液及全胚细胞悬液,经尾静脉注射于荷瘤小鼠(乳腺癌、纤维肉瘤、艾氏腹水痛)。观测移植瘤生长情况和支持机体存活时间的作用。结果:经实验观察及统计学处理、全胚细胞悬液及胚肝细胞悬液输注荷瘤小鼠均未见到抑瘤作用及支持机体延长寿命的作用。结论:我们的试验结果可能预示着细胞疗法对肿瘤的治疗是有限的,需进一步研究以便做出客观的评估。
OBJECTIVE: To investigate the effect of murine cell suspension and whole-cell suspension on tumor-bearing mice. METHODS: In this experiment, embryonic liver cells, suspensions and whole embryonic cell suspensions from the second trimester and second trimester of TA2 mice were injected via the tail vein into tumor-bearing mice (breast cancer, fibrosarcoma, and Ehrlich ascites pain). Observe the growth of transplanted tumors and support the survival of the body. RESULTS: No significant anti-tumor effect and longevity of the body were observed after experimental observation and statistical analysis, whole embryonic cell suspensions and embryonic liver cell suspension infusion of tumor-bearing mice. Conclusion: Our results may indicate that cell therapy is limited to the treatment of tumors and further studies are needed to make an objective assessment.