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选择１２例过敏性哮喘患者为研究对象，２０例正常人为对照．应用逆向人嗜碱粒细胞脱颗粒试验检测嗜碱粒细胞释放能力和免疫放射法测定血清总ＩｇＥ，观察过敏性哮喘息者在脱敏治疗前后嗜碱粒细胞释放能力和血清总ＩｇＥ的变化。实验结果显示：过敏性哮喘患者的嗜碱粒细胞释放能力和血清总ＩｇＥ显著高于正常人；脱敏治疗一年后，过敏性哮喘患者的嗜碱粒细胞释放能力显著降低，血清总ＩｇＥ水平虽有一定程度的降低，但无显著性差异。提示：长期脱敏治疗有助于稳定嗜碱粒细胞的功能。
Twelve patients with allergic asthma were selected as study subjects and 20 normal controls. The anti-basophil degranulation test was used to detect the release of basophil and the total IgE of serum was measured by immunoradioassay. The changes of basophil release and total serum IgE before and after desensitization were observed. The results showed that the basophil release capacity and serum total IgE in patients with allergic asthma were significantly higher than those in normal people. After one year of desensitization treatment, the basophil release capacity of allergic asthma patients was significantly decreased, the serum total IgE level Although there is a certain degree of reduction, but no significant difference. Tip: Long-term desensitization treatment helps stabilize basophil function.