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抗痉挛药物的药理学1857年 Locock 推荐用溴化钾治疗癫痫。1912年发现巴比土类的效果,至1937年起选用苯妥英钠于癫痫大发作的治疗,并在1945年推荐三甲双酮用于癫痫小发作,但于
Pharmacology of antispasmodic drugs Locock recommended the treatment of epilepsy with potassium bromide in 1857. The effect of barbiturates was discovered in 1912 and phenytoin sodium was used in the treatment of epileptic seizures until 1937. Trimethadione was recommended in 1945 for the treatment of epileptic seizures but at