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止血凝血机制发生障碍在临床上表现为两大类疾患,一类是由于止血、凝血功能低下所致的出血性疾患,另一类为其功能亢进所致的血栓栓塞性疾病,本文只介绍出血性疾患的实验诊断。出血性疾患是指以不正常出血为主要表现的一大组疾患,即是指无明显诱因而发生皮肤、粘膜或深部组织的出血,或仅受轻微创伤却出血不止。出血性疾患的发病机理十分复杂,但可概括为以下几大方面:①微血管壁的结构或功能异常;②血小板数量减少或功能障碍;③凝血因子含量或活性减低;④血循环中抗凝物质增多;⑤以上各方面的综合缺陷如急性弥漫性血管内凝血(DIC)。以下就这几方面进行讨论。
Hemostatic coagulation mechanism of obstacles in the clinical manifestations of two major types of diseases, one is due to hemostasis, coagulation disorders caused by bleeding disorders, and the other is its hyperthyroidism caused by thromboembolic diseases, this article describes only bleeding Experimental diagnosis of sexual disorders. Hemorrhagic disorder refers to a large group of disorders characterized by abnormal bleeding, which refers to the bleeding of the skin, mucous membranes or deep tissues without obvious predisposition, or bleeding with more minor trauma. The pathogenesis of hemorrhagic disorders is very complex, but can be summarized as the following major aspects: ① microvascular wall structure or dysfunction; ② reduce the number of platelets or dysfunction; ③ clotting factor content or activity decreased; ④ blood circulation increased anticoagulant substances ; ⑤ comprehensive defects in all aspects such as acute diffuse intravascular coagulation (DIC). The following discussion on these aspects.