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对９～１６岁佝偻病７９例、健康对照６１例进行临床及生化研究，结果：①肢体疼痛、无力、多汗、抽搐等是青春期佝偻病的主要临床表现。②有相当一部分患儿为无临床表现的隐性佝偻病。③佝偻病组血钙显著低于对照组。④骨碱性磷酸酶（ＢＡＬＰ）与总碱性磷酸酶（ＴＡＬＰ）高度直线相关，两者在佝偻病组均显著高于对照组，ＴＡＬＰ在正常对照组中女孩１３岁、男孩１６岁开始下降。⑤血２５（ＯＨ）Ｄ浓度对照组高于佝偻病组，低于服维生素Ｄ组。⑥血磷、血甲状旁腺素（ＰＴＨ）在佝偻病组和对照组间未见显著性差异。
79 cases of 9 ~ 16 years old rickets and 61 cases of healthy control were studied in clinic and biochemistry. Results: ① limb pain, weakness, hyperhidrosis, convulsions and so on were the main clinical manifestations of adolescent rickets. ② There are a considerable number of children with clinical manifestations of recessive rickets. ③ rickets group serum calcium was significantly lower than the control group. ④ Bone alkaline phosphatase (BALP) and total alkaline phosphatase (TALP) were highly linear, both in rickets group were significantly higher than the control group, TALP in the normal control group, the girl was 13 years old, the boy began to decline at 16 years old. ⑤ blood 25 (OH) D concentration in the control group was higher than rickets, lower than taking vitamin D group. ⑥ blood phosphorus, blood parathyroid hormone (PTH) in rickets and control group no significant difference.