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目的:观察健脑化瘤汤联合化疗治疗脑部恶性肿瘤的临床疗效。方法:选取符合条件的脑癌患者76例为研究对象,随机分为试验组和对照组,每组38例,试验组以健脑化瘤汤加VD化疗方案,对照组单用VD化疗方案,观察2组近期临床疗效、临床症状积分变化、卡氏评分的变化以及不良反应的发生情况。结果:试验组总有效率为44.73%,对照组总有效率为31.57%,2组间比较,差异无统计学意义(P>0.05)。治疗后,2组患者的症状体征积分明显降低、卡氏评分上升,与治疗前比较,差异均有统计学意义(P<0.05);与对照组治疗后比较,试验组症状体征积分和卡氏评分改善的更明显,差异均有统计学意义(P<0.05)。呕吐、骨髓抑制等不良反应,试验组少于对照组,2组比较,差异有统计学意义(P<0.05)。结论:健脑化瘤汤联合化疗治疗脑部恶性肿瘤有确切临床疗效,可以改善患者生存质量,健脑化瘤汤对化疗可起到增效减毒作用。
Objective: To observe the clinical effect of brain tumor soup combined with chemotherapy in the treatment of malignant brain tumors. Methods: Sixty-six eligible patients with brain cancer were selected as study subjects and randomly divided into experimental group and control group, with 38 cases in each group. The experimental group was treated with brain tumor solution plus VD chemotherapy and the control group with VD chemotherapy alone. 2 groups of recent clinical efficacy, clinical symptom score changes, changes in the card’s score and the occurrence of adverse reactions. Results: The total effective rate was 44.73% in the experimental group and 31.57% in the control group. There was no significant difference between the two groups (P> 0.05). After treatment, the symptom and symptom scores of two groups were significantly decreased, and the Karnofsky’s scores increased, compared with those before treatment, the differences were statistically significant (P <0.05). Compared with the control group, The score improved more significantly, the differences were statistically significant (P <0.05). Vomiting, bone marrow suppression and other adverse reactions, the experimental group less than the control group, the two groups, the difference was statistically significant (P <0.05). Conclusion: Combined treatment of brain tumor soup and chemotherapy in the treatment of malignant tumors of the brain have a definite clinical effect, can improve the quality of life of patients, brain tumor soup can play a synergistic effect attenuated by chemotherapy.