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采用微量荧光测定法对20例哮喘患儿及35例健康儿童进行血清维生素A(Vit A)检测。结果表明:各年龄段哮喘患儿血清Vit A水平明显低于正常对照组,尤其是≤3岁组及>6岁组(P<0.001)。哮喘组亚临床Vit A缺乏发生率为80％(16/20例),正常对照组为20.8％(1/35例),有显著性差异(P<0.005)。其中≤3岁组最高,占50.0％(10/20例)。结论:儿童哮喘存在着亚临床状态Vit A缺乏,两者可能互为因果关系。
Serum vitamin A (Vit A) was detected in 20 asthmatic children and 35 healthy children by using microfluorometry. The results showed that the levels of serum VitA in children with asthma at all ages were significantly lower than those in the normal controls, especially those ≤3 years and> 6 years (P <0.001). The incidence of subclinical Vit A deficiency in asthma group was 80% (16/20) and that in normal control group was 20.8% (1/35), with significant difference (P <0.005). Among them, the group ≤3 years old was the highest, accounting for 50.0% (10/20 cases). Conclusion: There is subclinical Vit A deficiency in childhood asthma, both of which may be causal relationship with each other.