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目的观察丹参酮IIA磺酸钠治疗糖尿病下肢血管病变疗效。方法选择2型糖尿病下肢血管病变患者142例,随机分为两组。在常规应用口服降糖药物或胰岛素治疗的基础上,使用阿司匹林、甲钴胺、西洛他唑,治疗组加用丹参酮IIA80mg加入生理盐水250mL中静脉滴注,每日1次;对照组加用脉络宁20mL入生理盐水250mL中静脉滴注,每日1次,疗程均为2～3周。结果治疗组总有效率87.5%,与对照组比较差异均有显著性(P<0.05)。结论丹参酮IIA治疗糖尿病下肢血管病变是一种有效的方法。
Objective To observe the curative effect of tanshinone IIA sulfonate on diabetic lower extremity vascular disease. Methods 142 cases of type 2 diabetes mellitus with vascular disease were randomly divided into two groups. In the conventional application of oral antidiabetic drugs or insulin therapy, based on the use of aspirin, mecobalamin, cilostazol, the treatment group with tanshinone IIA80mg added 250mL of normal saline intravenously once a day; control group with Mailuoning 20mL 250mL normal saline infusion, 1 day, treatment are 2 to 3 weeks. Results The total effective rate in the treatment group was 87.5%, which was significantly different from that in the control group (P <0.05). Conclusion Tanshinone IIA treatment of diabetic lower extremity vascular lesions is an effective method.