目的探讨尼莫地平对高血压脑出血的血肿吸收及神经功能恢复的影响。方法选择发病24h内入院的高血压脑出血患者72例,随机分为尼莫地平组和对照组。两组均给予常规治疗,尼莫地平组应用尼莫地平注射液10mg/d,连续用10d后,改为口服或胃管注入40mg/次,3次/d,共用1个月。分别比较两组患者治疗后的血肿量、水肿面积及CSS评分。结果治疗2周后尼莫地平组血肿量和水肿面积均较对照组小,差异有统计学意义(P<0.05);治疗2周后尼莫地平组CSS评分低于对照组,差异有统计学意义(P<0.05),治疗1个月和3个月后两组的差异更加明显(P<0.01)。结论尼莫地平早期应用于高血压脑出血的治疗有利于血肿的吸收和减轻脑水肿,改善脑出血患者的预后。 Objective To investigate the effect of nimodipine on hematoma absorption and neurological recovery in hypertensive intracerebral hemorrhage. Methods 72 cases of hypertensive intracerebral hemorrhage admitted within 24 hours after onset were randomly divided into nimodipine group and control group. Both groups were given conventional treatment. The nimodipine group was given nimodipine injection 10mg / d continuously for 10 days, changed to oral or gastric tube injection 40mg / time, 3 times / d for 1 month. The hematoma volume, edema area and CSS score were compared between the two groups after treatment. Results After 2 weeks of treatment, the hematoma volume and edema area in the nimodipine group were smaller than those in the control group (P <0.05). After 2 weeks of treatment, the CSS scores of nimodipine group were lower than those in the control group (P <0.05). After one month and three months treatment, the differences between the two groups were more obvious (P <0.01). Conclusion The early application of nimodipine in the treatment of hypertensive intracerebral hemorrhage is conducive to the absorption of hematoma and reduce cerebral edema, and improve the prognosis of patients with intracerebral hemorrhage.