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目的:分析社区治疗慢性阻塞性肺部疾病(COPD)的抗生素成本-效果。方法:对COPD急性加重期使用抗菌药治疗的病人的临床资料进行回顾性整理和分析。结果:临床治疗有效率选用环丙沙星和红霉素联合的为86.36%,选用头孢呋辛的为84.62%,差异无统计学意义,而成本-效果分别为0.53和0.99。结论:在一般治疗基础上,联合使用环丙沙星和红霉素性价比高,治疗COPD急性加重期病人疗效较好,值得在社区医疗中推广。
Objective: To analyze the cost-effectiveness of antibiotics in community-based treatment of chronic obstructive pulmonary disease (COPD). Methods: The clinical data of patients treated with antimicrobial agents in acute exacerbation of COPD were retrospectively reviewed and analyzed. Results: The effective rate of clinical treatment with ciprofloxacin combined with erythromycin was 86.36%, with cefuroxime as 84.62%, the difference was not statistically significant, while the cost-effectiveness was 0.53 and 0.99 respectively. Conclusion: On the basis of general treatment, the combination of ciprofloxacin and erythromycin is cost-effective. The treatment of patients with acute exacerbation of COPD has better curative effect and is worthy of promotion in community medical care.