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目的观察间苯三酚与氧化亚氮联合应用于第一产程活跃期的效果。方法将120例初产妇随机分为间苯三酚与氧化亚氮联合应用组(观察1组,40例),单用间苯三酚组(观察2组,40例)和不用药物组(对照组,40例)。结果间苯三酚可显著缩短活跃期时间(P<0.01),间苯三酚与氧化亚氮联合应用既可明显缩短活跃期时间,还可达到良好的分娩镇痛疗效(P<0.01)。应用间苯三酚和氧化亚氮后产后2小时出血量、新生儿评分无显著改变(均P>0.05)。结论间苯三酚与氧化亚氮联合应用于第一产程活跃期有明显的缩短产程和镇痛作用。
Objective To observe the effect of combination of phloroglucinol and nitrous oxide on the active stage of the first stage of labor. Methods 120 cases of primipara were randomly divided into the group of phloroglucinol and nitrous oxide (observation group 1, 40 cases), single phloroglucinol group (observation group 2, 40 cases) and no drug group Group, 40 cases). Results The results showed that phloroglucinol could shorten the active period (P <0.01). The combination of phloroglucinol and nitrous oxide significantly shortened the active period and achieved satisfactory analgesia efficacy (P <0.01). Application of phloroglucinol and nitrous oxide after 2 hours of postpartum hemorrhage, no significant change in neonatal scores (all P> 0.05). Conclusion The combination of phloroglucinol and nitrous oxide in the active stage of the first stage of labor significantly shortened the labor process and analgesic effect.