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目的探讨米非司酮与米索前列醇不同的给药方法终止10～14周妊娠的效果。方法将210例妊娠10～14周要求终止妊娠的妇女随机分成两组,A组口服米非司酮25mg,q8h,首剂加倍,服完最后一片米非司酮后2小时口服米索0.6mg;B组顿服米非司酮200mg,12小时后阴道后穹窿放置米索0.6mg。结果两组流产成功率无差异,住院时间B组较A组明显缩短。结论米非司酮顿服200mg,12小时后阴道后穹窿放置米索0.6mg用于终止10～14周妊娠是一种有效的方法,可以明显缩短住院时间。
Objective To investigate the effect of different administration of mifepristone and misoprostol on the pregnancy of 10-14 weeks. METHODS: A total of 210 pregnant women who required termination of pregnancy during 10-14 weeks of gestation were randomly divided into two groups. Group A received mifepristone 25 mg q8h, and the first dose doubled. Two hours after the last dose of mifepristone, oral administration of 0.6 mg ; Group B Dayton mifepristone 200mg, 12 hours after the vaginal fornix placed misoprostol 0.6mg. Results There was no difference in the success rate of abortion between the two groups. The length of hospital stay in group B was significantly shorter than that in group A. Conclusion Mifepristone Dayton 200mg, 12 hours after vaginal posterior fornix placed 0.6mg misoprostol for the termination of 10 to 14 weeks of pregnancy is an effective method, can significantly reduce the length of stay.