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采用切断兔眼部分睫状后短动脉造成脉络膜缺血的动物模型，测定脉络膜血栓素Ｂ２（ＴｈｒｏｍｂｏｘａｎｅＢ２，ＴＸＢ２）和６－酮－前列腺素Ｆ１α（６－ｋｅｔｏ－ｐｒｏｓｔａｇｌａｎｄｉｎＦ１α，６－Ｋｅｔｏ－ＰＧＦ１ｄ）的含量，并观察复方樟柳碱１号（Ｃｏｍｐｏｕｎｄａｎｉｓｏｄｉｎｅ１，ＣＡ－１）对其影响。结果表明，缺血１ｈＴＸＢ２及６－Ｋｅｔｏ－ＰＧＦ１ｄ升高；２４ｈ时６－Ｋｅｔｏ－ＰＧＦ１α已呈下降趋势而ＴＸＢ２仍处于较高水平，使ＴＸＢ２／６－ｋｅｔｏ－ＰＧＦ１α比率升高。ＣＡ－１升高６－ｋｅｔｏ－ＰＧＦ１α并保持ＴＸＢ２和６－ｋｅｔｏ－ＰＧＦ１α之间的平衡。结果提示，缺血１ｈＴＸＢ２和６－ｋｅｔｏ－ＰＧＦ１α之间的平衡即发生变化；ＣＡ１－号改善缺血区脉络膜的微循环并可能调节缺血区血管紧张度。
The animal models of choroidal ischemia caused by the ciliary shortening of the ciliary tract were made. The levels of Thromboxane B2 (TXB2) and 6-keto-prostaglandin F1α (6-Keto-PGF1d) Content, and observe Compoundanisodine1 (Compoundanisodine1, CA-1) on the impact. The results showed that ischemic 1hTXB2 and 6-Keto-PGF1d increased; 6-Keto-PGF1α at 24 hours had a downward trend while TXB2 was still at a high level, so that TXB2 / 6-keto-PGF1α ratio increased. CA-1 elevates 6-keto-PGF1α and maintains a balance between TXB2 and 6-keto-PGF1α. The results suggest that the balance between ischemic 1hTXB2 and 6-keto-PGF1α changes; CA1- improves the microcirculation of the ischemic choroid and may regulate ischemic vascular tone.